Operational Planning Tool

Enrollment Forecast Calculator

Estimate clinical trial enrollment velocity, projected study completion timelines, and the referral volume required to meet enrollment targets on schedule. To understand which specific operational drivers — intake velocity, prescreening throughput, handoff quality, and enrollment rate consistency — contribute most to your timeline, see how enrollment operations impact study timelines.

Timeline projectionScenario comparisonRequired volume analysis

Enrollment Inputs

Adjust to reflect your site's referral volume, conversion rates, and study parameters.

80
50
12 mo

Conversion Rates

75%
65%
88%
92%

Enrollment Forecast

31.6

Monthly Enrollments

Participants reaching randomization per month

1.6

Months to Complete

At current enrollment velocity

39.5%

Referral Conversion

Referrals reaching randomization

11

Required Referrals/Mo

To hit target within study duration

On Track to Hit Target

At current velocity, enrollment target reached in 2 months vs. 12-month study duration.

Enrollment Velocity

High Velocity

Excellent velocity indicating highly optimized operations and strong pipeline management.

Monthly Enrollment Timeline

Cumulative enrollment progression at current velocity. Target reached when cumulative enrolled equals enrollment target.

MonthCumulative EnrolledProgress to Target
Month 131.6
Month 2Target50
Month 350
Month 450
Month 550
Month 650

Improvement Scenario Comparison

How changes to conversion rates or referral volume shift enrollment velocity and projected completion.

Current pace

31.6

enrollments/month

2 mo

to completion

+10% conversion improvement

+14.1/mo

All conversion rates ×1.10

45.7

enrollments/month

2 mo

to completion

+20% conversion improvement

+24.6/mo

All conversion rates ×1.20

56.2

enrollments/month

1 mo

to completion

+25% referral volume increase

+7.9/mo

Same conversion rates, more referrals

39.5

enrollments/month

2 mo

to completion

How to Use This Calculator

01

Enter your actual conversion rates

The calculator is only accurate when you enter your site's real performance data. Idealized rates produce misleading forecasts. Use actual intake completion percentages, prescreening pass rates, and scheduling success data from recent study operations.

02

Use the required referral output to identify supply gaps

The required referrals per month metric tells you how many monthly referrals are needed to hit your enrollment target on time. If this exceeds your current volume, you have a supply gap that must be addressed through increased referrals, improved conversion rates, or both.

03

Compare scenarios to choose your improvement path

The scenario comparison shows whether improving conversion rates or increasing referral volume will have a greater impact on your timeline. For most sites, conversion rate improvement produces faster gains with less external dependency. For the specific process levers that drive conversion improvement, see the guide on improving enrollment performance without increasing referrals.

04

Use stage-specific tools for deeper analysis

This calculator models four combined enrollment stages for timeline forecasting. For granular stage-by-stage loss analysis — including intake, handoff, scheduling, and consent stages — use the Referral to Randomization Calculator.

Frequently Asked Questions

Common questions about enrollment forecasting and how to use this calculator.

If your enrollment forecast reveals a timeline risk or performance gap, an Enrollment Alignment Call provides a direct review of your intake, prescreening, and coordinator capacity systems. If your forecast shows a conversion gap rather than a volume gap, see improving enrollment performance without increasing referrals for the process-level interventions that address it.

Need Help Improving Enrollment Velocity?